EGFR

English The Epidermal Growth Factor Receptor gene (EGFR) encodes a transmembrane glycoprotein, which belongs to the protein kinase superfamily. The protein binds to epidermal growth factors by the following mechanism: EFGR binds to the ligand Dimerization of the receptor and tyrosine autophosphorylation take place Cell proliferation occurs The mutation in exons 18, 19, 20 and 21 (which encode …