English
What is HER2?
HER2 is a transmembrane receptor with intrinsic tyrosine kinase activity. It belongs to the superfamily of epidermal growth factor receptors.
Overexpression of HER2 can lead to unabated kinase activity through either autodimerization or proteolysis.
Literature:
- Robbins and Cotran. Pathologic basis of disease. 9. Canada: Elsevier; 2015.
Patólogos sin fronteras 