This is an “under the microscope post” since we want you to obverse microscopic features.
English
Today’s post is about Hodgkin lymphoma: nodular sclerosis type.
The following slide shows core information about this neoplasia:
Now, it’s time to know how a lymph node looks like when it is affected by this type of tumour:
And this is what you find inside the nodules:
- Reed-Sternberg cells: they are malignant cells caused by B-lymphocites. They are large cells (45 µm in diameter) with multiple nuclei or only one nucleus with multiple nuclear lobes.
- Lacunar cells: they are a Reed-Sternberg cell variant that contains one or two nuclei in the middle of a lacuna (see the white hole in the picture above). This is because of the cytoplasm disruption occured during the cutting of sections.
- Robbins and Cotran. Pathologic basis of disease. 9. Canada: Elsevier; 2015.
Patólogos sin fronteras 